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Home / Archives for Plasmodium Falciparum

Malaria Prevention

April 20, 2012 By Malaria Q&A Leave a Comment

QUESTION What is malaria and the preventive measures? ANSWER Malaria is a disease caused by single-celled parasites of the genus Plasmodium. There are currently five species which cause disease in humans, and while each is slightly different, they all act in basically the same way, and cause similar symptoms. Of the five, the most dangerous is Plasmodium falciparum, which can lead to … [Read more...]

Filed Under: Malaria Q&A Tagged With: atovaquone-proguanil, Chemoprophylaxis, Chloroquine, Doxycycline, indoor residual spraying, Intermittent preventive therapy, Lariam, long-lasting insecticide treated bednets, Malarone, medication, Mefloquine, Plasmodium, Plasmodium Falciparum, travel medicine, vector prevention

Comparison of Molecular Tests for the Diagnosis of Malaria in Honduras

April 18, 2012 By Malaria.com 2 Comments

Honduras is a tropical country with more than 70% of its population living at risk of being infected with either Plasmodium vivax or Plasmodium falciparum. Laboratory diagnosis is a very important factor for adequate treatment and management of malaria. In Honduras, malaria is diagnosed by both, microscopy and rapid diagnostic tests and to date, no molecular methods have been implemented for … [Read more...]

Filed Under: Malaria Research Tagged With: Alexandre M De Oliveira, Engels Banegas, Gustavo A Fontecha, Honduras, Malaria Diagnosis, Malaria Diagnostics, Malaria Journal, Meisy Mendoza, Mitra Poorak, Molecular Tests, Naomi W Lucchi, Plasmodium Falciparum, Plasmodium Vivax, Rosa E Mejia, Tamara Mancero, Venkatachalam Udhayakumar

Malaria Prophylaxis in Ghana, Africa

April 14, 2012 By Malaria Q&A Leave a Comment

QUESTION My husband will be traveling to Ghana soon. We have Mefloquine and Primaquine. Which one do you think is best for prophylaxis in Ghana? He also has Fansidar, but we understand it's best not to use this for prophylaxis. Thank you for your help! ANSWER There are positives and negatives associated with both of these medications. Mefloquine is recommended for travelers in Ghana … [Read more...]

Filed Under: Malaria Q&A Tagged With: atovaquone-proguanil, Doxycycline, G6DP deficiency, Ghana, Malarone, Mefloquine, Plasmodium Falciparum, Plasmodium Vivax, Primaquine, prophylaxis, side effects, travel medicine

As American as…Plasmodium vivax?

April 14, 2012 By Claire Standley, Editor 1 Comment

While its evolutionary history is disputed, there’s no doubt malaria was a key factor in the history of the Americas I am in the midst of a fascinating book about the way the world changed after Columbus “discovered” America in 14921. Called, appropriately, 1493: Uncovering the World Columbus Created, it is author Charles C. Mann’s follow-up to an earlier, equally engaging book on pre-Colombian … [Read more...]

Filed Under: Blogs Tagged With: Anopheles, Britain, Carolina, Charles C Mann, Christopher Columbus, colonization, England, Evolution, evolutionary history, Genetics, Panama, Plasmodium Falciparum, Plasmodium simium, Plasmodium Vivax, Polynesia, Scotland, sequence analysis, slavery

Malaria Effects on the Body

April 11, 2012 By Malaria Q&A Leave a Comment

QUESTION What are the effects of malaria on the body? ANSWER Malaria has a number of effects on the body. The parasite passes from the blood (where it enters via the bite of an infected mosquito) into the liver, where it reproduces and changes form. After a period of 1-4 weeks (usually - it can be longer) in the liver, the malaria parasite re-enters the blood and begins to infect red … [Read more...]

Filed Under: Malaria Q&A Tagged With: Cerebral Malaria, immune response, liver stage, Malaria life cycle, malaria symtoms, Plasmodium Falciparum, Plasmodium Ovale, Plasmodium Vivax, Primaquine, red blood cell, relapse, sequestration, synchronous bursting

Reoccurring Malaria

April 8, 2012 By Malaria Q&A Leave a Comment

QUESTION Can malaria reoccur year after year from a single infection? I have been told that it comes back every year by many people. I have had malaria once and it never came back after successful treatment. My thinking is that once the parasite has been eliminated from the system it is gone unless you get bitten again. ANSWER There are several different types of malaria that infect … [Read more...]

Filed Under: Malaria Q&A Tagged With: blood stages, G6DP deficiency, liver stages, Malaria Symptoms, Malaria transmission, Plasmodium Falciparum, Plasmodium Ovale, Plasmodium Vivax, Plasmoidum knowlesi, Primaquine, relapse

Malaria Prevention

April 7, 2012 By Malaria Q&A Leave a Comment

QUESTION What are the ways in which you can prevent yourself from being infected with malaria? ANSWER Malaria prevention consists of a combination of mosquito avoidance measures (since malaria is transmitted by infected mosquitoes) and chemoprophylaxis (medication to prevent the establishment of malaria in your body, if you do get bitten). Although very efficacious, none of the … [Read more...]

Filed Under: Malaria Q&A Tagged With: Chemoprophylaxis, Chloroquine, Counterfeit Drugs, DEET, drug resistance, Fansidar, insect repellant, long-lasting insecticide treated bednets, long-sleeved clothing, malaria medication, Malaria transmission, Mefloquine, mosquito, Permethrin, Plasmodium Falciparum, Plasmodium Ovale, Plasmodium Vivax, Presumptive antirelapse therapy, prophylaxis, protective measures, screens, sulfadoxine-pyrimethamine, travel medicine, vector control

Herbal Treatment for Malaria

April 5, 2012 By Malaria Q&A Leave a Comment

QUESTION Can any form of malaria be treated by herbs or plants, and how long does it take to recover from malaria? ANSWER Actually, two of the most important kinds of anti-malarial medication are derived by substances found naturally in plants, though they need to be processed in certain ways before the full pharmaceutical effect is felt. Quinine, administered intravenously, is … [Read more...]

Filed Under: Malaria Q&A Tagged With: ACTs, Artemisinin, China, Cinchona, Malaria transmission, Plasmodium Falciparum, Plasmodium Knowlesi, Quinine, treatment, wormwood

Symtoms of Malaria

April 2, 2012 By Malaria Q&A Leave a Comment

QUESTION Please tell me the symptoms of malaria. ANSWER Symptoms of malaria include fever and flu-like illness, including shaking chills, headache, muscle aches, and tiredness. Due to the way in which the malaria parasite reproduces in the human body, fevers occurring in a cyclical fashion (i.e. high fever one day, no fever the next day, then recurrence of fever on the third or fourth … [Read more...]

Filed Under: Malaria Q&A Tagged With: Anaemia, Cerebral Malaria, coma, cyclical fever, Diarrhea, jaundice, Malaria life cycle, Malaria Symptoms, nausea, organ failure, Plasmodium Falciparum, vomiting

Prevention of Malaria

April 2, 2012 By Malaria Q&A Leave a Comment

QUESTION What is the prevention of malaria? ANSWER Malaria prevention consists of a combination of mosquito avoidance measures and chemoprophylaxis. Although very efficacious, none of the recommended interventions are 100% effective. Mosquito Avoidance Measures Because of the nocturnal feeding habits of Anopheles mosquitoes, malaria transmission occurs primarily between dusk and … [Read more...]

Filed Under: Malaria Q&A Tagged With: Anopheles, Chemoprophylaxis, Chloroquine-Resistant Malaria, insect repellent, long-lasting insecticide treated bednets, Malaria Control, Malaria Prevention, mosquito prevention, Plasmodium, Plasmodium Falciparum, prophylaxis, transmission, vector control

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WWARN Corner

About WWARN

The WorldWide Antimalarial Resistance Network (WWARN) generates innovative resources and reliable evidence to inform the malaria community on the factors affecting the efficacy of antimalarial medicines. Learn more…

  • Fighting Malaria Requires Protecting the Effectiveness of Antimalarial Medicines
  • Data Sharing at IDDO
  • Evidence to inform equitable dosing in very young and malnourished children

More WWARN Stories...

Five Things You Might Not Know About Medicine Quality

The proliferation of poor quality medicines has been described as a global pandemic that threatens the lives of millions.1 It stands to reason that poor quality medicines are not going to improve anyone’s health, but how much do we really know about the quality of medicines used across the world? Here we examine five issues relating to medicine quality in an effort to show why we should all be paying more attention to a serious public health issue that is difficult to tackle and not yet fully understood.

How Can We Detect Poor Quality Medicines?

Finding out what medicines contain and investigating their packaging are vital steps in the fight against poor quality medicines, both substandard and falsified. Falsified medicines usually masquerade as real medicines by copying the appearance and packaging of the real product, but may not contain any of the same active ingredients, or in the correct amounts.

Challenges in Tackling the Issue of Poor Quality Medicines

There are many unresolved issues that impede the elimination of poor quality medicines, namely: (1) Progress impeded by confusion over definitions; Ensuring a market free of poor quality medicines; and the lack of global criminal laws.

Editorial

Antimicrobial Resistance: The Silent Threat in Malaria Eradication

By Bernard Owusu Agyware, Arielle Dolegui and Jesus Aquilar Malaria is a serious and sometimes deadly disease, affecting millions and claiming more than  600,000 lives worldwide each year in 2022 and 2021.1 Low and Middle-Income Countries (LMICs), particularly in Sub-Saharan Africa, disproportionately bear the greatest burden of malaria. The fight to eradicate this worrisome disease […]

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