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Home / Archives for Plasmodium Falciparum

Intermittent Preventive Treatment for Malaria in Papua New Guinean Infants Exposed to Plasmodium falciparum and P. Vivax

March 28, 2012 By Malaria.com Leave a Comment

Intermittent preventive treatment in infants (IPTi) has been shown in randomized trials to reduce malaria-related morbidity in African infants living in areas of high Plasmodium falciparum (Pf) transmission. It remains unclear whether IPTi is an appropriate prevention strategy in non-African settings or those co-endemic for P. vivax (Pv). Methods and Findings In this study, 1,121 Papua New … [Read more...]

Filed Under: Malaria Research Tagged With: Artesunate, Papua New Guinea, Plasmodium Falciparum, Sanjeev Krishna, sulfadoxine-pyrimethamin

Malaria Symptoms

March 26, 2012 By Malaria Q&A Leave a Comment

QUESTION How does the virus cause the symptoms? ANSWER Malaria is actually not caused by a virus—it is caused by a microscopic single-celled parasite called Plasmodium. Several different species cause malaria in humans, the most common of which are P. vivax and P. falciparum. To describe the process in a very oversimplified way, the malaria parasites cause disease by infecting … [Read more...]

Filed Under: Malaria Q&A Tagged With: Anaemia, Cerebral Malaria, fever, haemoglobin, immune response, inflammation, parasite, Plasmodium, Plasmodium Falciparum, Plasmodium Vivax, red blood cells, sequestration, synchronised bursting

Malaria Testing

March 25, 2012 By Malaria Q&A Leave a Comment

QUESTION My daughter is in Kigoma, Tanzania and has the symptoms of Malaria. She was given Duo Cotecxin and it seems to have started making her feel better. But after reading up on all the different types of Malaria parasites I am wondering if a blood test reading at a clinic would be recommended or is it too late for an accurate reading now that she is on meds? ANSWER I am always very … [Read more...]

Filed Under: Malaria Q&A Tagged With: Duo-Cotecxin, hypnozoites, Kigoma, Malaria Diagnosis, Malaria Treatment, Plasmodium Falciparum, Plasmodium Ovale, Plasmodium Vivax, Primaquine, relapse, Tanzania

Duo-Cotecxin and Fansidar as Treatment

March 24, 2012 By Malaria Q&A 4 Comments

QUESTION My husband weighs and has malaria. He was told by the pharmacist to take 2 tablets stat, then 1 daily for five days followed by 3 Fansidar tablets. We live in Papua New Guinea. I see on the Duo-Cotecxin web site the dose is three tabs daily. Which is correct? ANSWER Fansidar is a very different drug to Duo-Cotecxin—it is made of a combination of sulfadoxine and … [Read more...]

Filed Under: Malaria Q&A Tagged With: ACTs, CDC, Duo-Cotecxin, Fansidar, Papua New Guinea, Plasmodium Falciparum, Plasmodium malariae, Plasmodium Ovale, Plasmodium Vivax, WHO

Repeated Malaria

March 17, 2012 By Malaria Q&A Leave a Comment

QUESTION Since January 2011 I got three times malaria. Is it come regularly? Last week also I got maleria and I took medicine but still I have mild headache and sweating feeling tiredenes in between.. ANSWER The timing of the repeated malaria episodes you have experienced means that it could be recrudescence (where treatment does not completely kill all the malaria parasites in your … [Read more...]

Filed Under: Malaria Q&A Tagged With: Artemisinin-based Combination Therapies, blood film, Chloroquine, chloroquine resistance, Coartem, Fansidar, indoor residual spraying, long-lasting insecticide treated bednets, Malaria Diagnosis, Malaria Prevention, microscopy, Plasmodium Falciparum, Plasmodium Ovale, Plasmodium Vivax, rapid diagnostic test, re-infection, recrudescence, relapse, sulfadoxine-pyrimethamine

Information About Malaria

March 16, 2012 By Malaria Q&A Leave a Comment

QUESTION What is malaria? ANSWER Malaria is a serious and sometimes fatal disease caused by a tiny parasite that commonly infects a certain type of mosquito (of the genus Anopheles) which feeds on humans. People who get malaria are typically very sick with high fevers, shaking chills, and flu-like illness. Four kinds of malaria parasites can infect humans: Plasmodium falciparum, P. vivax, … [Read more...]

Filed Under: Malaria Q&A Tagged With: Anopheles, Malaria causes, Malaria Symptoms, Plasmodium, Plasmodium Falciparum, Plasmodium malariae, Plasmodium Ovale, Plasmodium Vivax

Malaria’s Scientific Name

March 15, 2012 By Malaria Q&A Leave a Comment

QUESTION What is malaria's scientific name? ANSWER The genus name for the single-celled parasite which causes malaria is Plasmodium. In the genus, there are five species which infect humans: Plasmodium falciparum (the most deadly kind), P. vivax, P. ovale, P. malariae and P. knowlesi. … [Read more...]

Filed Under: Malaria Q&A Tagged With: malaria nomenclature, Plasmodium, Plasmodium Falciparum, Plasmodium Knowlesi, Plasmodium malariae, Plasmodium Ovale, Plasmodium Vivax, scientific name

Simulations Plus Announces Preliminary Success in Malaria Drug Design Project

March 15, 2012 By Malaria.com Leave a Comment

Simulations Plus, Inc., a provider of consulting services and software for pharmaceutical discovery and development, today announced that preliminary testing shows that one of the molecules it has designed to inhibit the malaria parasite has been shown to be a potent inhibitor of the malaria parasite. Dr. Robert Clark, director of life sciences for Simulations Plus, said: "We're excited to … [Read more...]

Filed Under: Malaria News Tagged With: ADME, ADMET Predictor, cheminformatics, Dr. Michael Lawless, Dr. Robert Clark, GastroPlus, Kalexsyn, MedChem Designer, MedChem Studio, Plasmodium Falciparum, Simulations Plus

Malaria Drug Binding Site

March 14, 2012 By Malaria Q&A Leave a Comment

QUESTION What is malaria, and drug binding site? ANSWER Malaria is caused by a single-celled protozoan parasite of the genus Plasmodium. Five kinds of Plasmodium are known to infect people: P. falciparum, P. vivax, P. ovale, P. malariae and P. knowlesi. There is no one drug binding site with respect to malaria: different anti-malarial drugs have different modes of action, and not all … [Read more...]

Filed Under: Malaria Q&A Tagged With: alkylating agents, Artemisinin, causes of malaria, cell death, Chloroquine, endoperoxide moiety, FP-Chloroquine complex, free radicals, heme, hemoglobin, hemozoin, mechanisms of anti-malarials, Plasmodium, Plasmodium Falciparum, Plasmodium Knowlesi, Plasmodium malariae, Plasmodium Ovale, Plasmodium Vivax, protozoan, single-celled

Celebral Malaria and Blindness

March 14, 2012 By Malaria Q&A Leave a Comment

QUESTION I live in Nigeria. Good friend of mine complained of headaches in Dec 2011. Did an MRI went to Germany had a general check up. Back in Nigeria in January, headaches increase, she gets blind in one eye, following day the other eye, now in Germany where they have induced her into a coma. They said that she got a brain Haemorrage from the malaria. Can malaria bring blindness. What are the … [Read more...]

Filed Under: Malaria Q&A Tagged With: blindness, brain hemorrhage, Cerebral Malaria, coma, Germany, Malaria Treatment, Nigeria, Plasmodium Falciparum, Quinine, recovery, severe malaria

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