The WorldWide Antimalarial Resistance Network (WWARN) generates innovative resources and reliable evidence to inform the malaria community on the factors affecting the efficacy of antimalarial medicines. About WWARN The WorldWide Antimalarial Resistance Network (WWARN) is a multi-disciplinary, scientifically independent network that provides reliable evidence to inform the malaria community … [Read more...]
Fighting Malaria Requires Protecting the Effectiveness of Antimalarial Medicines
Health advocates mark World Malaria Day this week with focus on elimination World Malaria Day is an opportunity to take stock in the battle against a disease which still kills approximately half a million people each year, most of them children under the age of five in Africa. We have made great progress in recent years, with the global death rate cut by almost 30% between 2010 and 2015, yet … [Read more...]
Data Sharing at IDDO
This video describes the data sharing approach taken at IDDO. … [Read more...]
Evidence to inform equitable dosing in very young and malnourished children
Effective treatment of malaria patients requires definition of the antimalarial concentrations required in patients’ blood to assure that they are cured. The doses needed to achieve these concentrations in most patients have been determined, but many factors can influence the drug exposure actually achieved even when the same weight-based (mg/kg) dose is given to each patient. The studies that … [Read more...]
Large scale study on indicators of ACT efficacy in Africa
A new study from WWARN’s ACT Africa Baseline Study Group finds that current indicators of the efficacy of ACT based on persistence of parasites in the first 3 days after treatment may need some adjustment for African populations, due to the differences in immunity between African and Asian populations. Slow parasite clearance – the rate at which malaria parasites decline in the patient’s … [Read more...]