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Home / Archives for immune response

Malaria Effects on the Body

April 11, 2012 By Malaria Q&A Leave a Comment

QUESTION What are the effects of malaria on the body? ANSWER Malaria has a number of effects on the body. The parasite passes from the blood (where it enters via the bite of an infected mosquito) into the liver, where it reproduces and changes form. After a period of 1-4 weeks (usually - it can be longer) in the liver, the malaria parasite re-enters the blood and begins to infect red … [Read more...]

Filed Under: Malaria Q&A Tagged With: Cerebral Malaria, immune response, liver stage, Malaria life cycle, malaria symtoms, Plasmodium Falciparum, Plasmodium Ovale, Plasmodium Vivax, Primaquine, red blood cell, relapse, sequestration, synchronous bursting

Malaria Symptoms

March 26, 2012 By Malaria Q&A Leave a Comment

QUESTION How does the virus cause the symptoms? ANSWER Malaria is actually not caused by a virus—it is caused by a microscopic single-celled parasite called Plasmodium. Several different species cause malaria in humans, the most common of which are P. vivax and P. falciparum. To describe the process in a very oversimplified way, the malaria parasites cause disease by infecting … [Read more...]

Filed Under: Malaria Q&A Tagged With: Anaemia, Cerebral Malaria, fever, haemoglobin, immune response, inflammation, parasite, Plasmodium, Plasmodium Falciparum, Plasmodium Vivax, red blood cells, sequestration, synchronised bursting

Malaria in Mosquitoes

March 10, 2012 By Malaria Q&A Leave a Comment

QUESTION Why can't mosquitoes become sick of malaria? What do they have in their system that prevent them from becoming sick yet they transmit the disease to humans? ANSWER First of all, mosquitoes do get "sick" when infected with malaria, though not in the same way as humans. This is due to the major differences between human and mosquito physiology and also differences in the life stage … [Read more...]

Filed Under: Malaria Q&A Tagged With: gametocytes, immune response, Malaria life cycle, mosquito, red blood cells, sporozoites

Malaria and Renal Failure

October 26, 2011 By Malaria Q&A Leave a Comment

QUESTION Explain how malaria can cause renal failure? ANSWER There are several mechanisms by which malaria can contribute to renal failure, which vary due to the type of malaria. The exact way in which these various effects combine to cause acute renal failure is not known. The most common type of malaria to cause renal failure is Plasmodium falciparum, generally the most severe and … [Read more...]

Filed Under: Malaria Q&A Tagged With: dehydration, deoxygenation, immune response, infected red blood cells, reduced blood flow, renal failure, sequestration, shock

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WWARN Corner

About WWARN

The WorldWide Antimalarial Resistance Network (WWARN) generates innovative resources and reliable evidence to inform the malaria community on the factors affecting the efficacy of antimalarial medicines. Learn more…

  • Fighting Malaria Requires Protecting the Effectiveness of Antimalarial Medicines
  • Data Sharing at IDDO
  • Evidence to inform equitable dosing in very young and malnourished children

More WWARN Stories...

Five Things You Might Not Know About Medicine Quality

The proliferation of poor quality medicines has been described as a global pandemic that threatens the lives of millions.1 It stands to reason that poor quality medicines are not going to improve anyone’s health, but how much do we really know about the quality of medicines used across the world? Here we examine five issues relating to medicine quality in an effort to show why we should all be paying more attention to a serious public health issue that is difficult to tackle and not yet fully understood.

How Can We Detect Poor Quality Medicines?

Finding out what medicines contain and investigating their packaging are vital steps in the fight against poor quality medicines, both substandard and falsified. Falsified medicines usually masquerade as real medicines by copying the appearance and packaging of the real product, but may not contain any of the same active ingredients, or in the correct amounts.

Challenges in Tackling the Issue of Poor Quality Medicines

There are many unresolved issues that impede the elimination of poor quality medicines, namely: (1) Progress impeded by confusion over definitions; Ensuring a market free of poor quality medicines; and the lack of global criminal laws.

Editorial

Antimicrobial Resistance: The Silent Threat in Malaria Eradication

By Bernard Owusu Agyware, Arielle Dolegui and Jesus Aquilar Malaria is a serious and sometimes deadly disease, affecting millions and claiming more than  600,000 lives worldwide each year in 2022 and 2021.1 Low and Middle-Income Countries (LMICs), particularly in Sub-Saharan Africa, disproportionately bear the greatest burden of malaria. The fight to eradicate this worrisome disease […]

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