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Home / Archives for Plasmodium Falciparum

KSHV Oral Shedding and Plasma Viremia Result in Significant Changes in the Extracellular Tumorigenic miRNA Expression Profile in Individuals Infected with the Malaria Parasite

February 9, 2018 By Malaria.com Leave a Comment

Kaposi's sarcoma herpesvirus (KSHV) is the etiological agent of Kaposi’s sarcoma (KS). Both KSHV and HIV infections are endemic in Uganda, where KS is among the most common cancers in HIV-infected individuals. Recent studies examined the use of small RNAs as biomarkers of disease, including microRNAs (miRNAs), with viral and tumor-derived miRNAs being detected in exosomes from individuals with … [Read more...]

Filed Under: Malaria Research Tagged With: Corey Casper, HIV, KSHV, Michael R. Dyen, Minako Ikoma, miRNA, Plasmodium Falciparum, PLoS One, Qing Zhang, Ryan Basom, Serge Barcy, Soren Gantt, Timothy M. Rose, Uganda, Yuko Ogata

Targeting NAD+ Metabolism in the Human Malaria Parasite Plasmodium falciparum

April 18, 2014 By Malaria.com Leave a Comment

Nicotinamide adenine dinucleotide (NAD+) is an essential metabolite utilized as a redox cofactor and enzyme substrate in numerous cellular processes. Elevated NAD+ levels have been observed in red blood cells infected with the malaria parasite Plasmodium falciparum, but little is known regarding how the parasite generates NAD+. Here, we employed a mass spectrometry-based metabolomic approach to … [Read more...]

Filed Under: Malaria Research Tagged With: Nicotinamide adenine dinucleotide (NAD+), Plasmodium Falciparum

What Body Systems are Affected by Malaria?

November 23, 2013 By Malaria Q&A Leave a Comment

Question: What tissues,organs and/or body systems are affected by malaria? Answer: The malaria parasite is transmitted through blood and has an immediate effect on red blood cells. The most common symptoms of malaria including fever, are caused when the parasites invade red blood cells (erythrocytes) and rupture.  However, there are five species of the Plasmodium parasite that cause … [Read more...]

Filed Under: Malaria Q&A Tagged With: Cerebral Malaria, Malaria Symptoms, Malaria transmission, Plasmodium Falciparum, red blood cells

Is malaria a blood borne pathogen?

November 18, 2013 By Malaria Q&A Leave a Comment

Question: Is malaria a bloodborne pathogen? Answer: Yes.  Malaria is caused by a single-celled parasite of the genus Plasmodium (there are five species which infect humans, being Plasmodium falciparum, P. vivax, P. ovale, P. malariae and P. knowlesi), introduced into the human blood stream through the bite of an infected anopheles mosquito. To learn more about how the malaria parasite … [Read more...]

Filed Under: Malaria Q&A Tagged With: Anopheles, Malaria transmission, Plasmodium, Plasmodium Falciparum, Plasmodium Knowlesi, Plasmodium malariae, Plasmodium Ovale, Plasmodium Vivax

What is the Malaria Parasite?

November 14, 2013 By Malaria Q&A Leave a Comment

Question: What is the malaria parasite? Answer: Malaria is caused by a single-celled parasite of the genus Plasmodium; there are five species which infect humans, being Plasmodium falciparum, P. vivax, P. ovale, P. malariae and P. knowlesi. All these species are introduced into the human blood stream through the bite of an infected female anopheles mosquito. … [Read more...]

Filed Under: Malaria Q&A Tagged With: Anopheles, Malaria transmission, mosquito, P. knowlesi, P. malariae, P. ovale, P.vivax, Plasmodium, Plasmodium Falciparum

Chorangiosis Implicated in Pregnant Women Infected with Malaria

April 23, 2013 By Malaria.com Leave a Comment

A passing remark launched the project that will be described at the Experimental Biology 2013 conference in Boston on Monday. A poster, presented by undergraduate Ashley McMichael from Albany State University, has preliminary data that hint that there is an association between a rare pregnancy condition and malaria. The remark that launched the project was made by a collaborator of Julie Moore, … [Read more...]

Filed Under: Malaria News Tagged With: Albany State University, American Society for Biochemistry and Molecular Biology, Ashley McMichael, Chorangiosis, Julie Moore, Plasmodium Falciparum, Pregnancy and Malaria

Is it Malaria Relapse?

February 4, 2013 By Malaria Q&A Leave a Comment

QUESTION WHILE IN VIETNAM, I HAD VIVAX AND FACIPRIUM MALARIA. THE OLDER I GET I COME DOWN WITH THE CHILLS, FEVER AND PROFUSE SWEATING. BLOOD TEST NEVER DOES SHOW ANY MALARIA BUT DOES SHOW THE VIVAX ANTIBODIES. DOES THIS MEAN I STILL HAVE MALARIA OR HOW LONG DO THE ANTIBODIES REMAIN IN MY BODY AND WHY NO MALARIA CELLS? ANSWER Antibodies to malaria can persist in the body for years after … [Read more...]

Filed Under: Malaria Q&A Tagged With: antibodies, diagnosis, Plasmodium Falciparum, Plasmodium Vivax, recurring malaria, relapse

Whole-plant Artemisia May Curtail Malaria Drug Resistance

December 19, 2012 By Malaria.com Leave a Comment

Malaria affects millions of people in the developing world each year, and fighting the disease can be difficult, because the  mosquito-borne parasite Plasmodium falciparum, which causes the deadliest form of malaria, has developed resistance to every anti-malaria drug. Molecular parasitologist Stephen Rich at the University of Massachusetts Amherst is leading a research team that has found a … [Read more...]

Filed Under: Malaria News Tagged With: Artemisia, Artemisia annua, Doug Golenbock, Mostafa Elfawal, Pamela Weathers, Plasmodium Falciparum, Stephen Rich, University of Massachusetts Amherst, Worcester Polytechnic Institute (WPI)

URGENT HELP ON MALARIA

September 17, 2012 By Malaria Q&A Leave a Comment

QUESTION I 25 yr old male from Lagos, Nigeria. I have been having frequent malaria since 2006 till present. My symptoms are always weakness of the body, feeling cold sometimes not always and also my mouth got better most cases. I have been to the hospital several times and the doctor told me my frequent malaria is because my blood genotype is AA and also am having a malaria parasites. I was … [Read more...]

Filed Under: Malaria Q&A Tagged With: artemisinin-based combination therapy, Chloroquine, Combisunate, indoor residual spraying, long-lasting insecticide-treated bednet, long-sleeved clothing, Malaria Diagnosis, Malaria Symptoms, Malaria Treatment, Nigeria, Plasmodium Falciparum

Malaria or Kidney Infection?

September 16, 2012 By Malaria Q&A Leave a Comment

QUESTION Two months ago my daughter was in Uganda working and when came back to the States she was hospitalized for 4 days with Malaria symptoms. Her tests came back negative they really didn't act like they knew how to treat this. They kept telling her they didn't know how to diagnosis Malaria. So they treated her for it. She now after 2 months is once again hospitalized with the same … [Read more...]

Filed Under: Malaria Q&A Tagged With: blood test, diagnosis, kidney infection, Plasmodium Falciparum, Plasmodium Ovale, Plasmodium Vivax, Primaquine, rapid diagnostic test, relapse, symptoms, travel medicine, treatment, tropical medicine, Uganda

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