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Home / Archives for Plasmodium

Malaria Parasite Classification

May 29, 2012 By Malaria Q&A Leave a Comment

QUESTION What is the classification of malaria? ANSWER Malaria is caused by a single celled protist of the genus Plasmodium. This genus is part of a Phylum of single-celled protist organisms called Apicomplexa. The Apicomplexans mostly posses an organ called an apicoplast, which is part of an apical structure designed to aid entry into a host cell. The Apicomplexa is split into two … [Read more...]

Filed Under: Malaria Q&A Tagged With: Aconoidasida, Apicomplexa, apicoplast, classification, Haemosporidia, life history, Plasmodiidae, Plasmodium, protista, protists, red blood cells, taxonomy

What is Malaria?

May 27, 2012 By Malaria Q&A Leave a Comment

QUESTION What is malaria? What is the parasite that causes malaria? ANSWER Malaria is a serious and sometimes fatal disease caused by a parasite, of the genus Plasmodium, that commonly infects a certain type of mosquito (of the genus Anopheles) which feeds on humans. People who get malaria are typically very sick with high fevers, shaking chills, and flu-like illness. Four kinds of … [Read more...]

Filed Under: Malaria Q&A Tagged With: Anopheles, parasite, Plasmodium, Plasmodium Falciparum, Plasmodium Knowlesi, Plasmodium malariae, Plasmodium Ovale, Plasmodium Vivax, symptoms

Structure and Size of Malaria

May 26, 2012 By Malaria Q&A Leave a Comment

QUESTION What is the structure and size of malaria? ANSWER Malaria is caused by a single celled protist of the genus Plasmodium. It undergoes a complex life cycle, involving two separate asexual reproductive stages in the vertebrate host (including humans) and sexual reproduction as well as multiplication in the insect vector (all human malaria is transmitted by mosquitoes). As such, the … [Read more...]

Filed Under: Malaria Q&A Tagged With: apicoplast, cell biology, DNA, life cycle, micotubules, mitochondrion, nucleus, Plasmodium, reproduction, structure

First Cases of Malaria

May 24, 2012 By Malaria Q&A Leave a Comment

QUESTION What is the first infected person with Plasmodium? ANSWER Plasmodium, the single-celled parasite which causes malaria, has been infecting humans since ancient times. In fact, the first written reference to its symptoms dates back almost 5000 years, to an ancient Chinese manuscript! It was also known from the writings of other ancient peoples, such as the Greeks, Romans and … [Read more...]

Filed Under: Malaria Q&A Tagged With: ancient chinese, Charles Louis Alphonse Laveran, Cinchona, Egyptians, Greeks, Malaria, native Americans, Plasmodium, Quinine, Romans

Vaccine for malaria? Differences with yellow fever?

May 12, 2012 By Malaria Q&A Leave a Comment

QUESTION Is there a vaccine to prevent malaria? What is the difference between yellow fever and malaria? ANSWER In answer to your first question, no, there is not currently a vaccine available to prevent malaria. The best current candidate, the RTS,S vaccine which was developed by GlaxoSmithKline, is currently undergoing Phase III clinical trials in Africa. Although preliminary results … [Read more...]

Filed Under: Malaria Q&A Tagged With: aches, burden, chills, control, eukaryote, fever, hemorrhagic fever, jaundice, morbidity, mortality, nausea, Plasmodium, protista, symptoms, treatment, vaccination, World Health Organization, yellow fever

Pathophysiology of Malaria

May 5, 2012 By Malaria Q&A Leave a Comment

QUESTION What is the pathophysiology of malaria? ANSWER Malaria causes disease through a number of pathways, which depend to a certain extent on the species. Malaria is caused by a single-celled parasite of the genus Plasmodium; there are five species which infect humans, beingPlasmodium falciparum, P. vivax, P. ovale, P. malariae and P. knowlesi. All these species are introduced into … [Read more...]

Filed Under: Malaria Q&A Tagged With: cyclic fever, erythrocytic cycle, exo-erythrocytic stage, life cycle, liver stage, Malaria transmission, merozoites, Plasmodium, Plasmodium Falciparum, Plasmodium Knowlesi, Plasmodium malariae, Plasmodium Ovale, Plasmodium Vivax, red blood cells, reproduction, sequestration, sporozoite, synchronized rupture

What Causes Malaria

May 4, 2012 By Malaria Q&A Leave a Comment

QUESTION What are the causes of malaria? ANSWER Malaria is caused  by infection with certain single-celled parasites of the genus Plasmodium. Specifically, there are five species which infect humans: P. falciparum (the most severe and dangerous form of malaria), P. vivax, P. ovale, P. malariae and P. knowlesi. The symptoms of the disease occur when the parasite enters the blood stream … [Read more...]

Filed Under: Malaria Q&A Tagged With: causes of malaria, Cerebral Malaria, life cycle, parasite, Plasmodium, Plasmodium Falciparum, Plasmodium Knowlesi, Plasmodium malariae, Plasmodium Ovale, Plasmodium Vivax, symptoms

Anopheles Mosquito

May 1, 2012 By Malaria Q&A 4 Comments

QUESTION Why is it only the female anopheles mosquito alone can cause malaria but not the male anopheles mosquito or any other mosquitoes? ANSWER Malaria is actually caused by a single-celled parasite called Plasmodium—it is transmitted via the bite of a female mosquito, of the genus Anopheles, as she takes a blood meal from a human (or other mammal) host. Male mosquitoes do not … [Read more...]

Filed Under: Malaria Q&A Tagged With: Aedes, black flies, blood meal, Culex, female, mosquito, Plasmodium, sand flies, transmission

Malaria Prevention

April 20, 2012 By Malaria Q&A Leave a Comment

QUESTION What is malaria and the preventive measures? ANSWER Malaria is a disease caused by single-celled parasites of the genus Plasmodium. There are currently five species which cause disease in humans, and while each is slightly different, they all act in basically the same way, and cause similar symptoms. Of the five, the most dangerous is Plasmodium falciparum, which can lead to … [Read more...]

Filed Under: Malaria Q&A Tagged With: atovaquone-proguanil, Chemoprophylaxis, Chloroquine, Doxycycline, indoor residual spraying, Intermittent preventive therapy, Lariam, long-lasting insecticide treated bednets, Malarone, medication, Mefloquine, Plasmodium, Plasmodium Falciparum, travel medicine, vector prevention

Prevention of Malaria

April 2, 2012 By Malaria Q&A Leave a Comment

QUESTION What is the prevention of malaria? ANSWER Malaria prevention consists of a combination of mosquito avoidance measures and chemoprophylaxis. Although very efficacious, none of the recommended interventions are 100% effective. Mosquito Avoidance Measures Because of the nocturnal feeding habits of Anopheles mosquitoes, malaria transmission occurs primarily between dusk and … [Read more...]

Filed Under: Malaria Q&A Tagged With: Anopheles, Chemoprophylaxis, Chloroquine-Resistant Malaria, insect repellent, long-lasting insecticide treated bednets, Malaria Control, Malaria Prevention, mosquito prevention, Plasmodium, Plasmodium Falciparum, prophylaxis, transmission, vector control

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WWARN Corner

About WWARN

The WorldWide Antimalarial Resistance Network (WWARN) generates innovative resources and reliable evidence to inform the malaria community on the factors affecting the efficacy of antimalarial medicines. Learn more…

  • Fighting Malaria Requires Protecting the Effectiveness of Antimalarial Medicines
  • Data Sharing at IDDO
  • Evidence to inform equitable dosing in very young and malnourished children

More WWARN Stories...

Five Things You Might Not Know About Medicine Quality

The proliferation of poor quality medicines has been described as a global pandemic that threatens the lives of millions.1 It stands to reason that poor quality medicines are not going to improve anyone’s health, but how much do we really know about the quality of medicines used across the world? Here we examine five issues relating to medicine quality in an effort to show why we should all be paying more attention to a serious public health issue that is difficult to tackle and not yet fully understood.

How Can We Detect Poor Quality Medicines?

Finding out what medicines contain and investigating their packaging are vital steps in the fight against poor quality medicines, both substandard and falsified. Falsified medicines usually masquerade as real medicines by copying the appearance and packaging of the real product, but may not contain any of the same active ingredients, or in the correct amounts.

Challenges in Tackling the Issue of Poor Quality Medicines

There are many unresolved issues that impede the elimination of poor quality medicines, namely: (1) Progress impeded by confusion over definitions; Ensuring a market free of poor quality medicines; and the lack of global criminal laws.

Editorial

Antimicrobial Resistance: The Silent Threat in Malaria Eradication

By Bernard Owusu Agyware, Arielle Dolegui and Jesus Aquilar Malaria is a serious and sometimes deadly disease, affecting millions and claiming more than  600,000 lives worldwide each year in 2022 and 2021.1 Low and Middle-Income Countries (LMICs), particularly in Sub-Saharan Africa, disproportionately bear the greatest burden of malaria. The fight to eradicate this worrisome disease […]

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