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Home / Archives for merozoites

Life Cycle of Malaria

May 22, 2012 By Malaria Q&A Leave a Comment

QUESTION Why does the malaria parasite first enter the liver? ANSWER The malaria parasite enters the liver in order to transform from a sporozoite (which can infect liver cells) to a merozoite, which is capable of infecting red blood cells. Both stages also include a proliferation step, but in the blood, the merozoites are also able to differentiate into gametocytes, which are then taken … [Read more...]

Filed Under: Malaria Q&A Tagged With: blood meal, constraints, Evolution, gametocytes, hepatocyte, life cycle, liver cells, merozoites, mosquito, red blood cells, sporozoites, transmission

Pathophysiology of Malaria

May 5, 2012 By Malaria Q&A Leave a Comment

QUESTION What is the pathophysiology of malaria? ANSWER Malaria causes disease through a number of pathways, which depend to a certain extent on the species. Malaria is caused by a single-celled parasite of the genus Plasmodium; there are five species which infect humans, beingPlasmodium falciparum, P. vivax, P. ovale, P. malariae and P. knowlesi. All these species are introduced into … [Read more...]

Filed Under: Malaria Q&A Tagged With: cyclic fever, erythrocytic cycle, exo-erythrocytic stage, life cycle, liver stage, Malaria transmission, merozoites, Plasmodium, Plasmodium Falciparum, Plasmodium Knowlesi, Plasmodium malariae, Plasmodium Ovale, Plasmodium Vivax, red blood cells, reproduction, sequestration, sporozoite, synchronized rupture

Irregular Quotidian Fever

December 17, 2011 By Malaria Q&A Leave a Comment

QUESTION Why quotidian fever is irregular? ANSWER Actually, the fever cycles associated with all types of malaria can be irregular. This is particular true in the initial stages of the fever, when the merozoites (the form of the parasite that leaves the liver to infect red blood cells) from different infection broods mature at different rates. Over a few cycles of reproduction, the … [Read more...]

Filed Under: Malaria Q&A Tagged With: asynchronous, emergence, irregular fever cycles, merozoites, Plasmodium Falciparum, quotidian, red blood cells

Do Sporozoites in blood signal the end of prepatent period?

November 4, 2011 By Malaria Q&A Leave a Comment

QUESTION Will the appearance of sporozoites in blood mark the end of prepatent period in malaria? ANSWER Actually, no. The presence of sporozoites indicates the start of the infection. Sporozoites are introduced into the bloodstream via the bite of an infected mosquit0. The sporozoites then have to make their way to the liver and infect hepatocyte cells, where they undergo … [Read more...]

Filed Under: Malaria Q&A Tagged With: asexual replication, budding, erythrocytes, hepatocytes, Malaria Symptoms, merozoites, pre-erythrocytic schizogony, pre-patent infection, sporozoites

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