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Home / Archives for antibodies

Is it Malaria Relapse?

February 4, 2013 By Malaria Q&A Leave a Comment

QUESTION WHILE IN VIETNAM, I HAD VIVAX AND FACIPRIUM MALARIA. THE OLDER I GET I COME DOWN WITH THE CHILLS, FEVER AND PROFUSE SWEATING. BLOOD TEST NEVER DOES SHOW ANY MALARIA BUT DOES SHOW THE VIVAX ANTIBODIES. DOES THIS MEAN I STILL HAVE MALARIA OR HOW LONG DO THE ANTIBODIES REMAIN IN MY BODY AND WHY NO MALARIA CELLS? ANSWER Antibodies to malaria can persist in the body for years after … [Read more...]

Filed Under: Malaria Q&A Tagged With: antibodies, diagnosis, Plasmodium Falciparum, Plasmodium Vivax, recurring malaria, relapse

Can the PCR blood test identify hypnozoites?

November 3, 2012 By Malaria Q&A 2 Comments

QUESTION I have never been diagnosed with malaria but returned from Turkey in 2007 (P. Vivax endemic area; Diarbykar & Mardin areas). My symptoms were consistent with malaria and I have now had 5 relapses since then, averaging one occurrence per year. I now have impaired kidney functioning and I am uncertain if this could be because of undiagnosed malaria? Would the PCR blood test at … [Read more...]

Filed Under: Malaria Q&A Tagged With: antibodies, diagnosis, dormant life stage, ELISA, endemic areas, hypnozoites, liver, PCR, Plasmodium Vivax, travelers

Testing for Dormant Malaria

September 17, 2012 By Malaria Q&A Leave a Comment

QUESTION When malaria is dormant in the body can it be detected in a blood test? ANSWER Not directly, no. A normal malaria blood test consists of a thick or thin smear, which is often stained and then looked at under a microscope; with these tests, you would not be able to see any sign of the malaria which is lying dormant in the liver. However, there is another type of blood test, known … [Read more...]

Filed Under: Malaria Q&A Tagged With: antibodies, immune system, infection, malaria test, Plasmodium Ovale, Plasmodium Vivax, serology, thick smear, thin smear

About Malaria Proteins

August 5, 2012 By Malaria Q&A Leave a Comment

QUESTION Please tell about about malarial causitive proteins. ANSWER I'm not sure what your question is, as malaria is not caused by a protein, but rather by a single-celled parasite called Plasmodium, which contains many different types of proteins. Some of these are indeed used for entering host cells and thus causing disease. Many of these proteins, and particularly ones on the surface … [Read more...]

Filed Under: Malaria Q&A Tagged With: antibodies, antigen, Duffy, immune system, parasite, Plasmodium Knowlesi, Plasmodium Vivax, protein

High Count of Malarial Antibodies

May 31, 2012 By Malaria Q&A Leave a Comment

QUESTION In 2007 we travelled to Kenya and Zanzibar. We took the normal anti-malarial tablets and were unaware of having been bitten. My older son has recently had a full medical and one of the blood tests which he had to repeat came back with a high count for malaria antibodies for Plasmodium falciparum. The doctor told him that he had had malaria at some time. We are puzzled as he has never … [Read more...]

Filed Under: Malaria Q&A Tagged With: acute infection, antibodies, blood smear, chronic, East Africa, Malaria Diagnosis, microscope, treatment

Persistent Antibodies to Malaria?

April 13, 2012 By Malaria Q&A 2 Comments

QUESTION I had malaria as child, more than 30 years ago. It was successfully treated with no relapse. I have since travelled to malaria- endemic countries, but the last time was over 3 years ago. No symptoms. I recently donated blood and routine screening has detected malaria antibodies. How long do the antibodies persist? ANSWER Based on your experience, I would say at least three years! … [Read more...]

Filed Under: Malaria Q&A Tagged With: acquired immunity, antibodies, Bednets, immune system, immunity, infection, Malaria Prevention, Malaria transmission, Screening, serological tests

Malaria and Pregnancy

April 9, 2012 By Malaria Q&A Leave a Comment

QUESTION Can your baby become immune if you're pregnant and you have malaria? ANSWER Some of the protective antibodies that the mother produces when she has malaria can pass to her baby via the placenta. There is also evidence for immune system "priming" in foetuses when their mothers have been infected my malaria during pregnancy. However, these potentially protective effects are usually … [Read more...]

Filed Under: Malaria Q&A Tagged With: abortion, Anaemia, antibodies, Bednets, congenital malaria, immune priming, immune suppression, Intermittent preventive therapy, IPTp, low birth weight, Malaria Prevention, placenta

Test for Malaria?

March 16, 2012 By Malaria Q&A Leave a Comment

QUESTION Is there a way to verify that someone has had malaria? I had symptoms that were treated with only 10 days of proper 14 days prescription and had a relapse a year later. Have felt weak and keep my drinking to a very light level as a result. Is there test that can be taken to verify having/had plasmodium vivax? ANSWER The best way to test for relapsing malaria (i.e. Plasmodium … [Read more...]

Filed Under: Malaria Q&A Tagged With: antibodies, blood film, ELISA, G6DP deficiency, Malaria Diagnosis, Plasmodium Vivax, Primaquine, rapid diagnostic test, relapse, serology

Late Malaria Confirmation

January 28, 2012 By Malaria Q&A Leave a Comment

QUESTION I was given a field diagnosis of malaria 1 1/2years ago and was treated. Can I still get a blood test to confirm if I truly had malaria? ANSWER That's a very interesting question, and the answer is: it depends. Since you were treated, you will no longer have the parasites in your blood stream, and so you cannot use a traditional blood film, looked at under a microscrope, which is … [Read more...]

Filed Under: Malaria Q&A Tagged With: antibodies, blood film, Malaria Diagnosis, microscopy, serology

Will Malaria Test Work with No Symptoms Present?

December 23, 2011 By Malaria Q&A Leave a Comment

QUESTION I believe my fiance who lives in Kenya has malaria but refuses to go for a test. She has headaches and now flu like symptoms. I am returning in late December, if the symptoms have gone can I still take her for a blood test to see if malaria is still present even if the symptoms subside? ANSWER Most malaria diagnosis in Kenya is done by looking at a small sample of the patient's … [Read more...]

Filed Under: Malaria Q&A Tagged With: antibodies, Kenya, Malaria Diagnosis, Malaria Treatment, microscopy, non-symptomatic malaria, Rapid Diagnostic Tests, symptomatic malaria

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