QUESTION Can malaria penetrate the brain? ANSWER Approximately 1% of people with malaria will develop a severe form, and in these cases the brain can be affected. When the brain is affected, the condition is called cerebral malaria. Functional changes to the blood-brain barrier occur in cerebral malaria, possibly as a result of the binding of parasitized red blood cells to … [Read more...]
Malaria: Should I See a Doctor?
QUESTION For the last couple of days I am suffering from all the symptoms that are mentioned on your website and I am taking tylenol for these symptoms thinking that it is flu but I am feeling better now. Should I still see a doctor or keep taking Tylenol? ANSWER Symptoms of malaria often include high fever, aches, chills, nausea, and headache. When severe, malaria can lead to anemia, … [Read more...]
Can Malaria Cause Blindness?
QUESTION Can you please help us? My husband got severe malaria and now he’s blind. He stayed 33 days in hospital. We live in Portugal. My husband came back from Africa (Angola) on 2nd June 2012. On 3rd June he started feeling ill. He got worse next days. The symptoms were strong headache, high fever, chills, delirium, vomit, couldn’t breathe and weakness. He went to hospital on 7th June. On … [Read more...]
Antimalarial Drugs During pPregnancy
QUESTION What is the safest antimalarial drug to be used by a pregnant woman in her second trimester? ANSWER With regards to treating malaria, intravenous artesunate (or quinine, if artesunate is not available) should be used for the treatment of severe/complicated Plasmodium falciparum malaria. Signs of severe and/or complicated malaria include impaired consciousness, organ failure, … [Read more...]
Duration of Malaria Symptoms
QUESTION If untreated how long will a person suffer symptoms caused by Malaria? ANSWER The answer to that depends a lot on what type of malaria they have as well as their own immune status, and particularly if they have been infected with malaria before. So, for example, P. falciparum is the most severe and deadly kind of malaria, and without treatment, many people who do not have … [Read more...]
Number of Species of Malaria
QUESTION I recently read an ISOS world malaria day poster saying 5 species of plasmodium cause malaria. I think that is confusing as we always talked about 4, ovale, vivax, falciparum and malaria....are they referring to the way we now split ovale into 2 sub species? or is this a typo on their part? ANSWER That is a really interesting question, and a good observation on your part! I … [Read more...]
QUESTION What are the of different types of antimalaria drugs? ANSWER Most drugs used in treatment are active against the parasite forms in the blood (the form that causes disease) and include: chloroquine atovaquone-proguanil (Malarone®) artemether-lumefantrine (Coartem®) artesunate-pyronaridine (Pyramax®) dihydroartemisinin-piperaquine (Duo-Cotecxin®) mefloquine … [Read more...]
Celebral Malaria and Blindness
QUESTION I live in Nigeria. Good friend of mine complained of headaches in Dec 2011. Did an MRI went to Germany had a general check up. Back in Nigeria in January, headaches increase, she gets blind in one eye, following day the other eye, now in Germany where they have induced her into a coma. They said that she got a brain Haemorrage from the malaria. Can malaria bring blindness. What are the … [Read more...]
Why not create a vaccine for malaria?
QUESTION Why not create a vaccine for malaria? ANSWER There are many teams of scientists working hard to try to produce a malaria vaccine. In fact, only last year, the preliminary results of a vaccine trial were published. The vaccine, called RTS,S, has been produced by GlaxoSmithKline and is in the midst of Phase III trials in Africa. The preliminary results showed approximately a … [Read more...]
Thalassaemia and Malaria
QUESTION How can Thalassaemia effect Malaria infection? ANSWER Thalassaemia is the name given to a group of inherited genetic blood disorders, which result in reduced or no synthesis of one of the globin protein chains that combine to make haemaglobin. Haemaglobin is used to carry oxygen throughout the body and to its organs. Thalassaemia can result in anaemia; in some cases, this is … [Read more...]