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Home / Archives for PCR

Can the PCR blood test identify hypnozoites?

November 3, 2012 By Malaria Q&A 2 Comments

QUESTION I have never been diagnosed with malaria but returned from Turkey in 2007 (P. Vivax endemic area; Diarbykar & Mardin areas). My symptoms were consistent with malaria and I have now had 5 relapses since then, averaging one occurrence per year. I now have impaired kidney functioning and I am uncertain if this could be because of undiagnosed malaria? Would the PCR blood test at … [Read more...]

Filed Under: Malaria Q&A Tagged With: antibodies, diagnosis, dormant life stage, ELISA, endemic areas, hypnozoites, liver, PCR, Plasmodium Vivax, travelers

What Cell count defines malaria?

November 2, 2012 By Malaria Q&A Leave a Comment

QUESTION What Cell count defines malaria?? ANSWER If you are referring to the cell count for diagnosis, then really the answer is that if ANY malaria parasites are observed in a blood film, then the slide should be considered positive for malaria. Of course, some people can have low levels of parasite in their blood, which are not easily detected under a microscope, using a blood slide. … [Read more...]

Filed Under: Malaria Q&A Tagged With: blood slide, Malaria Diagnosis, microscopy, PCR, rapid diagnostic test, RDT

Malaria Detection

January 14, 2012 By Malaria Q&A Leave a Comment

QUESTION what's the newest form of malaria detection? ANSWER While the traditional form of malaria detection has been through microscopy of a blood film slide, two new technologies have recently emerged. The first is the use of reagent strips, which are impregnated with molecules that bind to various other proteins present in the blood during a malaria infection. These reagent strips are … [Read more...]

Filed Under: Malaria Q&A Tagged With: blood film, diagnostic tests, Malaria Diagnosis, microscopy, PCR, polymerase chain reaction, rapid diagnostic test, RDTs

Malaria with Eye Pain

November 21, 2011 By Malaria Q&A Leave a Comment

QUESTION I am having malaria with severe eye pains. What is this? ANSWER Have you actually been diagnosed with malaria, or do you just think you have malaria based on the symptoms? If the latter, I would suggest you visit the doctor immediately. Eye pain is not usually associated with malaria (beyond the fact that some headaches manifest behind the eyes), whereas eye pain is a common … [Read more...]

Filed Under: Malaria Q&A Tagged With: dengue fever, eye pain, flu-like illness, Malaria Symptoms, nausea, PCR, rash, tourniquet test, white blood cell count

Diagnostic test for malaria?

September 13, 2011 By Malaria Q&A Leave a Comment

QUESTION: What are the possible diagnoses tests? ANSWER: A blood test is usually required to diagnose malaria, although the blood can be used in a number of different ways. The most common, traditional form of diagnosis is a blood smear, observed under a microscope by a qualified technician. These can be "thick" or "thin"; the "thick" smear examines a whole drop of blood for the presence … [Read more...]

Filed Under: Malaria Q&A Tagged With: blood smear, Malaria Diagnosis, microscopy, PCR, Rapid Diagnostic Tests, sensitivity, specificity

Do I have malaria?

June 8, 2011 By Malaria Q&A 2 Comments

QUESTION: Hi, I went to Ivory Coast August/2003 back March/2004, took some pills to help prevent Malaria on my trip but ran out and did not get more. While I was there I got many mosquito bites. Around October/03 became very sick, got tested for malaria at the hospital in Quebec but negative. Now May/2011 still have all the same symptoms, flu like symptoms, feeling cold most of the time, … [Read more...]

Filed Under: Malaria Q&A Tagged With: Chloroquine, Malaria Diagnosis, Malaria relapse, Malaria Symptoms, PCR, Plasmodium Falciparum, Plasmodium malariae, Plasmodium Ovale, primequine, RDTs

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WWARN Corner

About WWARN

The WorldWide Antimalarial Resistance Network (WWARN) generates innovative resources and reliable evidence to inform the malaria community on the factors affecting the efficacy of antimalarial medicines. Learn more…

  • Fighting Malaria Requires Protecting the Effectiveness of Antimalarial Medicines
  • Data Sharing at IDDO
  • Evidence to inform equitable dosing in very young and malnourished children

More WWARN Stories...

Five Things You Might Not Know About Medicine Quality

The proliferation of poor quality medicines has been described as a global pandemic that threatens the lives of millions.1 It stands to reason that poor quality medicines are not going to improve anyone’s health, but how much do we really know about the quality of medicines used across the world? Here we examine five issues relating to medicine quality in an effort to show why we should all be paying more attention to a serious public health issue that is difficult to tackle and not yet fully understood.

How Can We Detect Poor Quality Medicines?

Finding out what medicines contain and investigating their packaging are vital steps in the fight against poor quality medicines, both substandard and falsified. Falsified medicines usually masquerade as real medicines by copying the appearance and packaging of the real product, but may not contain any of the same active ingredients, or in the correct amounts.

Challenges in Tackling the Issue of Poor Quality Medicines

There are many unresolved issues that impede the elimination of poor quality medicines, namely: (1) Progress impeded by confusion over definitions; Ensuring a market free of poor quality medicines; and the lack of global criminal laws.

Editorial

Antimicrobial Resistance: The Silent Threat in Malaria Eradication

By Bernard Owusu Agyware, Arielle Dolegui and Jesus Aquilar Malaria is a serious and sometimes deadly disease, affecting millions and claiming more than  600,000 lives worldwide each year in 2022 and 2021.1 Low and Middle-Income Countries (LMICs), particularly in Sub-Saharan Africa, disproportionately bear the greatest burden of malaria. The fight to eradicate this worrisome disease […]

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