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Home / Archives for Artemisinin

Traditional Treatments for Malaria

November 15, 2013 By Malaria Q&A Leave a Comment

QUESTION What are some traditional treatments for malaria? ANSWER Many different cultures have had their own traditional ways of treating malaria. Perhaps the two best known come from the native tribes in the Western Amazon basin and the ancient Chinese. Tribes in the Amazon used the bark of a shrub called Cinchona to treat fevers and shivering; Spanish priests in this region observed … [Read more...]

Filed Under: Malaria Q&A Tagged With: ACTs, Artemisinin, Artemisinin-based Combination Therapies, Chloroquine, Quinine, traditional medicine

World Health Organization Seeks Funding for Emergency Response to Drug-resistant Malaria

October 27, 2013 By Steve Herman Leave a Comment

BANGKOK — The World Health Organization is warning that about $450 million is needed over the next three years to stop a strain of drug-resistant malaria from spreading beyond Southeast Asia to the rest of the world. Researchers say the artemisinin-resistant strain has spread to Burma and Vietnam since it was first detected along the Cambodian-Thai border in 2008. In addition to sounding the … [Read more...]

Filed Under: Malaria News Tagged With: Artemisinin, Burma, Eva-Maria Christophel, Vietnam, World Health Organization (WHO)

Scientists Describe Breakthrough in Anti-Malarial Precurser

April 11, 2013 By Malaria.com Leave a Comment

Scientists from Amyris published in the journal Nature the details of a major breakthrough in the field of synthetic biology that allows for the production of a key precursor to Artemisinin, the key ingredient in the world’s most effective and preferred drug in combating malaria. Earlier today, pharmaceutical company Sanofi announced the launch of large-scale industrial production of Artemisinin … [Read more...]

Filed Under: Malaria News Tagged With: ACT, Amyris, Artemisinin, John Melo, OneWorld Health, Sanofi

Medicine for Malaria

September 16, 2012 By Malaria Q&A Leave a Comment

QUESTION is rotam and maladar malaria medicine? ANSWER I have never heard of Rotam, but Maladar is the brand name of a combination sulfadoxine-pyrimethamine, and is used to treat malaria. However, it should be noted that it is not recommended by the World Health Organization as a first-line treatment option, due to concerns about drug resistance, and also lack of efficacy against certain … [Read more...]

Filed Under: Malaria Q&A Tagged With: artemether, Artemisinin, Artemisinin-based Combination Therapies, Coartem, Duo-Cotecxin, Lonart, lumefantrine, Maladar, Malaria Treatment, Mefloquine, piperaquine, sulfadoxine-pyrimethamine, World Health Organization

Chemists Develop New Synthesis for Antimalarial Drug, Artemisinin

September 13, 2012 By Malaria.com Leave a Comment

Chemists at Indiana University have developed a new synthesis for the world's most useful antimalarial drug, artemisinin, giving hope that fully synthetic artemisinin might help reduce the cost of the live-saving drug in the future. Effective deployment of ACT, or artemisinin-based combination therapy, has been slow due to high production costs of artemisinin. The World Health Organization has … [Read more...]

Filed Under: Malaria News Tagged With: ACT, Artemisinin, Chunyin Zh, cyclohexenone, Journal of the American Chemical Society, Silas Cook

Malaria in Pakistan

September 10, 2012 By Malaria Q&A Leave a Comment

QUESTION 4 years ago I traveled to FATA Pakistan and in every year in the month of August I caught malaria. Last few days I feel much Headache and fever in the evening and go to doctor. He diagnosed malarial parasites in blood and has advised me take tab artem ds 2 BD for three days after complete the course I feel same headache fever with shivering. Please recommend something. ANSWER I … [Read more...]

Filed Under: Malaria Q&A Tagged With: Artemisinin, drug resistance, recrudescence, relapse, side effects, treatment, World Health Organization

First in Malaria: U.S. or China?

August 31, 2012 By Malaria Q&A Leave a Comment

QUESTION Who discovered the world's first malaria vaccine? Is it the US marines in Washington DC or the People's Republic of China? ANSWER Unfortunately there is still no effective malaria vaccine.  You might be referring to the race between the US and China to find an effective malarial treatment during the Vietnam War years.  Currently, artemisinins, from the wormwood plant, discovered … [Read more...]

Filed Under: Malaria Q&A Tagged With: Artemisinin, China, Malaria Vaccine

New Treatment for Malaria

May 19, 2012 By Malaria Q&A Leave a Comment

QUESTION New treatment for malaria? ANSWER The most recently developed type of treatment for malaria actually has very ancient origins. The herb wormwood (Artemisia annua) has been used in ancient Chinese medicine for hundreds, even thousands, of years to cure certain fevers. In the 1970s, a Chinese research program intensively sought new medications against malaria, as part of their … [Read more...]

Filed Under: Malaria Q&A Tagged With: ACTs, Artemisia annua, Artemisinin, Chinese medicine, Chloroquine, Coartem, Duo-Cotecxin, lumefantrine, piperaquine, Pyramax, Pyronaridine, resistance, treatment research, wormwood

Herbal Treatment for Malaria

April 5, 2012 By Malaria Q&A Leave a Comment

QUESTION Can any form of malaria be treated by herbs or plants, and how long does it take to recover from malaria? ANSWER Actually, two of the most important kinds of anti-malarial medication are derived by substances found naturally in plants, though they need to be processed in certain ways before the full pharmaceutical effect is felt. Quinine, administered intravenously, is … [Read more...]

Filed Under: Malaria Q&A Tagged With: ACTs, Artemisinin, China, Cinchona, Malaria transmission, Plasmodium Falciparum, Plasmodium Knowlesi, Quinine, treatment, wormwood

Malaria Drug Binding Site

March 14, 2012 By Malaria Q&A Leave a Comment

QUESTION What is malaria, and drug binding site? ANSWER Malaria is caused by a single-celled protozoan parasite of the genus Plasmodium. Five kinds of Plasmodium are known to infect people: P. falciparum, P. vivax, P. ovale, P. malariae and P. knowlesi. There is no one drug binding site with respect to malaria: different anti-malarial drugs have different modes of action, and not all … [Read more...]

Filed Under: Malaria Q&A Tagged With: alkylating agents, Artemisinin, causes of malaria, cell death, Chloroquine, endoperoxide moiety, FP-Chloroquine complex, free radicals, heme, hemoglobin, hemozoin, mechanisms of anti-malarials, Plasmodium, Plasmodium Falciparum, Plasmodium Knowlesi, Plasmodium malariae, Plasmodium Ovale, Plasmodium Vivax, protozoan, single-celled

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