QUESTION What is the life cycle of malaria? ANSWER Malaria is caused by a single celled organism in the genus Plasmodium. Five species of Plasmodium infect humans, but all follow a very similar life cycle, including two separate cycles of asexual reproduction in the human host (one in the liver, called the exo-erythrocytic cycle, and one in the blood, and specifically inside red blood … [Read more...]
Three Stages of Malaria
QUESTION What are the three stages of malaria? ANSWER The three parts of the malaria life cycle are known as the exo-erythrocytic cycle, the erythrocytic cycle and the sporogonic cycle. The first two of these take place in the human (or other mammal) host, while the third occurs in the mosquito vector. The below diagram, courtesy of the CDC, shows the complete life cycle of malaria in … [Read more...]
Schizont
QUESTION What is a schizont? ANSWER A schizont is a malaria parasite which has matured and contains many merozoites, which are the parasite stage that infects red blood cells. Schizonts can be produces during two separate phases of the life cycle within the human host: first in the hepatocytic cells in the liver (when sporozoites mature) during the exo-erythrocytic cycle and then … [Read more...]
Pathophysiology of Malaria
QUESTION What is the pathophysiology of malaria? ANSWER Malaria causes disease through a number of pathways, which depend to a certain extent on the species. Malaria is caused by a single-celled parasite of the genus Plasmodium; there are five species which infect humans, being Plasmodium falciparum, P. vivax, P. ovale, P. malariae and P. knowlesi. All these species are introduced into … [Read more...]