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Home / Archives for Malaria evolution

Evolution of Malaria

March 2, 2012 By Malaria Q&A Leave a Comment

QUESTION how did malaria evolve? ANSWER Malaria in humans probably evolved independently several times, and both times likely due to a cross-over event from a closely related primate malaria. For example, Plasmodium vivax is evolutionarily closely related to several species of malaria found in macaque monkeys in south-east Asia, and so a cross-over of one of those species into human, with … [Read more...]

Filed Under: Malaria Q&A Tagged With: Aedes, Anopheles, bats, birds, biting midges (Culicoides), chimpanzees, Culex, Culiseta, gorillas, Haemoproteus, Hepatocystis, hippos, Leucocytozoon, lizards, louse flies (Hippoboscidae), macaque, Malaria evolution, Mansonia, mosquitoes, non-human primates, Plasmodium, Plasmodium Falciparum, Plasmodium reichenowi, Plasmodium Vivax, Psorophora, rodents, Simulium, tabanids (Tabanidae)

How long has malaria existed?

April 27, 2011 By Malaria Q&A Leave a Comment

QUESTION: How long has malaria been going on? ANSWER: The answer to your question depends on the kind of malaria as well as how exactly you define 'malaria'. The parasites which cause all forms of malaria, in humans as well as other mammals and birds, belong to a group called Plasmodium; scientists believe, based on genetic information, that this genus evolved around 130 million years … [Read more...]

Filed Under: Malaria Q&A Tagged With: Apicomplexa, Malaria evolution, Plasmodium, Plasmodium Falciparum, Plasmodium malariae, Plasmodium Ovale, Plasmodium Vivax

How did malaria start?

April 19, 2011 By Malaria Q&A 1 Comment

QUESTION: When did malaria happen? ANSWER: It is believed that Plasmodium, the parasite which causes malaria in a wide variety of animals, first evolved in reptiles. Even today, reptiles are infected by species of Plasmodium that are related to those that infect humans. The parasite probably then evolved to infect birds, and then, more recently, to infect mammals. Many mammals can be … [Read more...]

Filed Under: Malaria Q&A Tagged With: Malaria evolution, Non-human/Zoonotic Malaria, Plasmodium Falciparum

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WWARN Corner

About WWARN

The WorldWide Antimalarial Resistance Network (WWARN) generates innovative resources and reliable evidence to inform the malaria community on the factors affecting the efficacy of antimalarial medicines. Learn more…

  • Fighting Malaria Requires Protecting the Effectiveness of Antimalarial Medicines
  • Data Sharing at IDDO
  • Evidence to inform equitable dosing in very young and malnourished children

More WWARN Stories...

Five Things You Might Not Know About Medicine Quality

The proliferation of poor quality medicines has been described as a global pandemic that threatens the lives of millions.1 It stands to reason that poor quality medicines are not going to improve anyone’s health, but how much do we really know about the quality of medicines used across the world? Here we examine five issues relating to medicine quality in an effort to show why we should all be paying more attention to a serious public health issue that is difficult to tackle and not yet fully understood.

How Can We Detect Poor Quality Medicines?

Finding out what medicines contain and investigating their packaging are vital steps in the fight against poor quality medicines, both substandard and falsified. Falsified medicines usually masquerade as real medicines by copying the appearance and packaging of the real product, but may not contain any of the same active ingredients, or in the correct amounts.

Challenges in Tackling the Issue of Poor Quality Medicines

There are many unresolved issues that impede the elimination of poor quality medicines, namely: (1) Progress impeded by confusion over definitions; Ensuring a market free of poor quality medicines; and the lack of global criminal laws.

Editorial

Antimicrobial Resistance: The Silent Threat in Malaria Eradication

By Bernard Owusu Agyware, Arielle Dolegui and Jesus Aquilar Malaria is a serious and sometimes deadly disease, affecting millions and claiming more than  600,000 lives worldwide each year in 2022 and 2021.1 Low and Middle-Income Countries (LMICs), particularly in Sub-Saharan Africa, disproportionately bear the greatest burden of malaria. The fight to eradicate this worrisome disease […]

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