Abstract: Metarhizium anisopliae infects mosquitoes through the cuticle and proliferates in the hemolymph. To allow M. anisopliae to combat malaria in mosquitoes with advanced malaria infections, we produced recombinant strains expressing molecules that target sporozoites as they travel through the hemolymph to the salivary glands. Eleven days after a Plasmodium-infected … [Read more...]
The Dominant Anopheles Vectors of Human Malaria in Africa, Europe and the Middle East
Full Title The Dominant Anopheles Vectors of Human Malaria in Africa, Europe and the Middle East: Occurrence Data, dDstribution Maps and Bionomic Précis Background This is the second in a series of three articles documenting the geographical distribution of 41 dominant vector species (DVS) of human malaria. The first paper addressed the DVS of the Americas and the third will consider those … [Read more...]
Soil-Transmitted Helminths and Malaria in Pregnant Women on the Thai-Burmese Border
Background: Deworming is recommended by the WHO in girls and pregnant and lactating women to reduce anaemia in areas where hookworm and anaemia are common. There is conflicting evidence on the harm and the benefits of intestinal geohelminth infections on the incidence and severity of malaria, and consequently on the risks and benefits of deworming in malaria affected populations. We examined … [Read more...]
Screening Mosquito House Entry Points as a Potential Method for Integrated Control of Malaria
Partial mosquito-proofing of houses with screens and ceilings has the potential to reduce indoor densities of malaria mosquitoes. We wish to measure whether it will also reduce indoor densities of vectors of neglected tropical diseases. Methodology: The main house entry points preferred by anopheline and culicine vectors were determined through controlled experiments using specially … [Read more...]