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Development of Transgenic Fungi That Kill Human Malaria Parasites in Mosquitoes

January 19, 2011 By Malaria.com Leave a Comment

Abstract: Metarhizium anisopliae infects mosquitoes through the cuticle and proliferates in the hemolymph. To allow M. anisopliae to combat malaria in mosquitoes with advanced malaria infections, we produced recombinant strains expressing molecules that target sporozoites as they travel through the hemolymph to the salivary glands. Eleven days after a Plasmodium-infected … [Read more...]

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