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Home / Archives for RTSS Vaccine

RTS,S Malaria Vaccine Phase III Trial Results Show Promise, Though Diminished Effectiveness Over Time

April 27, 2015 By Malaria.com Leave a Comment

Final results from a large-scale Phase III trial of the RTS,S malaria vaccine candidate, including the impact of a booster dose, published today in The Lancet, show that the vaccine candidate helped protect children and infants from clinical malaria for at least three years after first vaccination. … [Read more...]

Filed Under: Malaria News Tagged With: GlaxoSmithKline, Malaria Vaccine, PATH Malaria Vaccine Initiative (MVI), RTS-S, RTSS Vaccine

GlaxoSmithKline Applies for Approval of RTS,S Malaria Vaccine

July 29, 2014 By Steve Baragona Leave a Comment

A “pretty good” malaria vaccine is on track to be the first to market. It only prevents infection about one-quarter to one-half the time, so it’s not as good as most vaccines. But for a disease like malaria, which kills 600,000 people a year, “pretty good” may be good enough. GlaxoSmithKline has applied for regulatory approval for its RTS,S vaccine. Partial protection A new 18-month study in … [Read more...]

Filed Under: Malaria News Tagged With: GlaxoSmithKline, Malaria Vaccine, RTSS Vaccine

GlaxoSmithKline Seeks to Market RTS,S Malaria Vaccine

October 8, 2013 By Malaria.com Leave a Comment

British drugmaker GlaxoSmithKline is seeking approval to market the world's first malaria vaccine, after trials showed that it significantly cut cases of the disease in children. Results from latest clinical trial of the RTS,S vaccine were unveiled at a conference in Durban, South Africa on Tuesday. It showed that after 18 months of follow-up, the vaccine halved the number of malaria cases … [Read more...]

Filed Under: Malaria News Tagged With: GlaxoSmithKline, Malaria Vaccine, RTSS Vaccine, VOA

Phase III Trial of RTS,S Malaria Candidate Vaccine Reduces Malaria by One Third

November 9, 2012 By Malaria.com Leave a Comment

Results from a pivotal, large-scale Phase III trial, published online today in the New England Journal of Medicine, show that the RTS,S malaria vaccine candidate can help protect African infants against malaria. When compared to immunization with a control vaccine, infants (aged 6-12 weeks at first vaccination) vaccinated with RTS,S had one-third fewer episodes of both clinical and severe malaria … [Read more...]

Filed Under: Malaria News Tagged With: Andrew Witty, Bill & Melinda Gates Foundation, Bill Gates, David Kaslow, GlaxoSmithKline, Malaria Vaccine, PATH Malaria Vaccine Initiative (MVI), RTSS Vaccine, Salim Abdulla

Glaxo’s RTS,S Malaria Vaccine Shows Promise

October 19, 2011 By Malaria.com Leave a Comment

Preliminary results from the trial of a malaria vaccine show that it protected nearly half of the children who received it from bouts of serious malaria, scientists said Tuesday. The vaccine, known as RTS,S and made by GlaxoSmithKline, has been in development for more than 25 years, initially for the American military and now with most of its support from the Bill and Melinda Gates Foundation. … [Read more...]

Filed Under: Malaria News Tagged With: Bill & Melinda Gates Foundation, Gates Foundation, GlaxoSmithKline, Malaria Vaccine, RTSS Vaccine

Study Finds Malaria Vaccine Candidate, RTS,S Significantly Reduces Malaria Risk in African Infants

October 18, 2011 By Malaria.com Leave a Comment

First results from a large-scale Phase III trial of RTS,S*, published online today in the New England Journal of Medicine (NEJM), show the malaria vaccine candidate to provide young African children with significant protection against clinical and severe malaria with an acceptable safety and tolerability profile. The results were announced today at the Malaria Forum hosted by the Bill & … [Read more...]

Filed Under: Malaria News Tagged With: Agenus Inc., Antigenics Inc., Bill & Melinda Gates Foundation, Francis Martinson, GlaxoSmithKline, Irving Hoffman, Malawi, PATH Malaria Vaccine Initiative (MVI), QS-21 Stimulon, RTSS Vaccine

RTS,S Malaria Vaccine

October 8, 2011 By Malaria Q&A 10 Comments

QUESTION: What information can you provide on this vaccine candidate? ANSWER: RTS,S is a vaccine candidate against Plasmodium falciparum malaria which works by encouraging the host's body to produce antibodies and T cells which diminish the malaria parasite's ability to survive and reproduce in the liver. Produced by GlaxoSmithKline, RTS,S is the first vaccine candidate against … [Read more...]

Filed Under: Malaria Q&A Tagged With: antibody productive, Bill & Melinda Gates Foundation, Gates Foundation, GlaxoSmithKline, Malaria Vaccine, Malaria Vaccine Initiative, PATH Malaria Vaccine Initiative (MVI), Phase III clinical trials, Plasmodium Falciparum, RTSS Vaccine

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About WWARN

The WorldWide Antimalarial Resistance Network (WWARN) generates innovative resources and reliable evidence to inform the malaria community on the factors affecting the efficacy of antimalarial medicines. Learn more…

  • Fighting Malaria Requires Protecting the Effectiveness of Antimalarial Medicines
  • Data Sharing at IDDO
  • Evidence to inform equitable dosing in very young and malnourished children

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